Crick-Jacobs Center for Theoretical and Computational Biology

Representative Publications:

McConnell, M.J., MacMillan, H.R., and J. Chun. (2009). Mathematical modeling supports substantial mouse neural progenitor cell death. Neural Development. 4: 28.

McConnell, M.J.*, Huang. Y.H.*, Datwani, A. and C.J. Shatz. (2009). H2-Kb and H2-Db regulate cerebellar long term depression and limit motor learning. Proceedings of the National Academy of Sciences USA. 106(16): 6784-6789.

Olson, S., Blanchette, M., Park, J., Savva, Y., Yeo, G.W., Yeakley, J.M., Rio, D.C., Graveley, B.R. A regulator of Dscam mutually exclusive splicing fidelity. Nature Structural & Molecular Biology 2007

Yeo, G.W., Xu, X, Liang, T.Y., Muotri, A.R., Carson, C.T., Coufal, N.G., Gage, F.H. Alternative Splicing Events Identified in Human Embryonic Stem Cells and Neural Progenitors. PLoS Computational Biology 2007

Calabrese J.M., Seila A.C., Yeo, G.W., Sharp P.A. RNA sequence analysis defines Dicer's role in mouse embryonic stem cells. Proc Natl Acad Sci U S A. 2007 Nov 7; [Epub ahead of print]

Giorgi, C., Yeo, G.W., Stone M.E., Katz D.B, Burge C., Turrigiano G., Moore M.J., The EJC Factor eIF4AIII Modulates Synaptic Strength and Neuronal Protein Expression. 2007, Cell 130 (179-191). (PDF)

Van Praag, H., Lucero, M.J., Yeo, G.W., Stecker, K.,Heivand, N., Zhao, C., Yip, E., Afanador, M., Schroeter, H., Hammerstone, J., Gage, F.H., Plant-Derived Flavanol (–)Epicatechin Enhances Angiogenesis and Retention of Spatial Memory in Mice. The Journal of Neuroscience, May 30, 2007, 27(22):5869-5878.

Yeo, G.W., Van Nostrand E. L., Liang, T. Y., Discovery and Analysis of Evolutionarily Conserved Intronic Splicing Regulatory Elements. PLOS Gen. 2007 Vol. 3(5): 814-829. (PDF)

Callaway EM. 2005 , A molecular and genetic arsenal for systems neuroscience. Trends Neurosci. 28:196-201.

Coggan, J. S., Bartol, T. M., Esquenazi, E., Stiles, J. R., Lamont, S., Martone, M. E., Berg, D. K., Ellisman, M. H., and Sejnowski, T. J., 2005, Evidence for ectopic neurotransmission at a neuronal synapse, Science, 39, 446-451

Venkatesh B, Lu SQ, Dandona N, See SL, Brenner S, Soong TW., 2005, Genetic basis of tetrodotoxin resistance in pufferfishes, 2005 , Curr Biol. 15:2069-72.

Yeo, G.W., Splicing regulators: targets and drugs. 2005, Genome Biol. 2005;6(12):240

Stevens, C.F., Preserving properties of object shape by computations in primary visual cortex. Proc Natl Acad Sci U S A., 2004, 101(43):15524-9